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Crystallization and X-ray diffraction analysis of the HMG domain of the chondrogenesis master regulator Sox9 in complex with a ChIP-Seq-identified DNA element

Sox9 is a fundamental sex-determining gene and the master regulator of chondrogenesis, and is involved in the development of various vital organs such as testes, kidney, heart and brain, and in skeletal development. Similar to other known Sox transcription factors, Sox9 recognizes and binds DNA with...

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Detalhes bibliográficos
Publicado no:Acta Crystallogr F Struct Biol Commun
Main Authors: Vivekanandan, Saravanan, Moovarkumudalvan, Balasubramanian, Lescar, Julien, Kolatkar, Prasanna R.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631595/
https://ncbi.nlm.nih.gov/pubmed/26527273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X1501969X
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