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ChIP-chip versus ChIP-seq: Lessons for experimental design and data analysis

BACKGROUND: Chromatin immunoprecipitation (ChIP) followed by microarray hybridization (ChIP-chip) or high-throughput sequencing (ChIP-seq) allows genome-wide discovery of protein-DNA interactions such as transcription factor bindings and histone modifications. Previous reports only compared a small...

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Detalhes bibliográficos
Main Authors: Ho, Joshua WK, Bishop, Eric, Karchenko, Peter V, Nègre, Nicolas, White, Kevin P, Park, Peter J
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3053263/
https://ncbi.nlm.nih.gov/pubmed/21356108
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1471-2164-12-134
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