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Systematic evaluation of factors influencing ChIP-seq fidelity

We performed a systematic evaluation of how variations in sequencing depth and other parameters influence interpretation of Chromatin immunoprecipitation (ChIP) followed by sequencing (ChIP-seq) experiments. Using Drosophila S2 cells, we generated ChIP-seq datasets for a site-specific transcription...

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Detalhes bibliográficos
Main Authors: Chen, Yiwen, Negre, Nicolas, Li, Qunhua, Mieczkowska, Joanna O., Slattery, Matthew, Liu, Tao, Zhang, Yong, Kim, Tae-Kyung, He, Housheng Hansen, Zieba, Jennifer, Ruan, Yijun, Bickel, Peter J., Myers, Richard M., Wold, Barbara J., White, Kevin P., Lieb, Jason D., Liu, X. Shirley
Formato: Artigo
Idioma:Inglês
Publicado em: 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3477507/
https://ncbi.nlm.nih.gov/pubmed/22522655
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nmeth.1985
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