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Crystallization and X-ray diffraction analysis of the HMG domain of the chondrogenesis master regulator Sox9 in complex with a ChIP-Seq-identified DNA element

Sox9 is a fundamental sex-determining gene and the master regulator of chondrogenesis, and is involved in the development of various vital organs such as testes, kidney, heart and brain, and in skeletal development. Similar to other known Sox transcription factors, Sox9 recognizes and binds DNA with...

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Dades bibliogràfiques
Publicat a:Acta Crystallogr F Struct Biol Commun
Autors principals: Vivekanandan, Saravanan, Moovarkumudalvan, Balasubramanian, Lescar, Julien, Kolatkar, Prasanna R.
Format: Artigo
Idioma:Inglês
Publicat: International Union of Crystallography 2015
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4631595/
https://ncbi.nlm.nih.gov/pubmed/26527273
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X1501969X
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