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Cloning, purification and preliminary X-ray data analysis of the human ID2 homodimer

The ID proteins are named for their role as inhibitors of DNA binding and differentiation. They contain a helix–loop–helix (HLH) domain but lack a basic DNA-binding domain. In complex with basic HLH (bHLH) transcription factors, gene expression is regulated by DNA-binding inactivation. Although the...

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Detalhes bibliográficos
Main Authors: Wong, Marie V., Palasingam, Paaventhan, Kolatkar, Prasanna R.
Formato: Artigo
Idioma:Inglês
Publicado em: International Union of Crystallography 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3515380/
https://ncbi.nlm.nih.gov/pubmed/23143248
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S174430911203895X
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