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Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of recombinant human fumarase

Human fumarase (HsFH) is a well-known citric acid cycle enzyme and is therefore a key component in energy metabolism. Genetic studies on human patients have shown that polymorphisms in the fumarase gene are responsible for diseases such as hereditary leiomyomatosis and renal cell cancer. As a first...

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Bibliografski detalji
Glavni autori: Pereira de Pádua, Ricardo Augusto, Nonato, Maria Cristina
Format: Artigo
Jezik:Inglês
Izdano: International Union of Crystallography 2013
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3943092/
https://ncbi.nlm.nih.gov/pubmed/24419633
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X13033955
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