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Cloning, expression, purification, crystallization and preliminary X-ray diffraction analysis of recombinant human fumarase
Human fumarase (HsFH) is a well-known citric acid cycle enzyme and is therefore a key component in energy metabolism. Genetic studies on human patients have shown that polymorphisms in the fumarase gene are responsible for diseases such as hereditary leiomyomatosis and renal cell cancer. As a first...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
International Union of Crystallography
2013
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3943092/ https://ncbi.nlm.nih.gov/pubmed/24419633 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1107/S2053230X13033955 |
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