A carregar...
Interaction between DNA Polymerase λ and Anticancer Nucleoside Analogs
The anticancer activity of cytarabine (AraC) and gemcitabine (dFdC) is thought to result from chain termination after incorporation into DNA. To investigate their incorporation into DNA at atomic level resolution, we present crystal structures of human DNA polymerase λ (Pol λ) bound to gapped DNA an...
Na minha lista:
| Main Authors: | , , , |
|---|---|
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Biochemistry and Molecular Biology
2010
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2878035/ https://ncbi.nlm.nih.gov/pubmed/20348107 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.094391 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|