PUMA mediates EGFR tyrosine kinase inhibitor-induced apoptosis in head and neck cancer cells

Overexpression of epidermal growth factor receptor (EGFR) is found in over 80% of head and neck squamous cell carcinomas (HNSCC) and associated with poor clinical outcomes. EFGR selective tyrosine kinase inhibitors (TKIs) or antibodies have recently emerged as promising treatments for solid tumors,...

Täydet tiedot

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Bibliografiset tiedot
Päätekijät: Sun, Q, Ming, L, Thomas, SM, Wang, Y, Chen, ZG, Ferris, RL, Grandis, JR, Zhang, L, Yu, J
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: 2009
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Article
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC2872091/
https://ncbi.nlm.nih.gov/pubmed/19421143
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2009.108
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