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Synergistic inhibition of head and neck tumor growth by green tea (−)-epigallocatechin-3-gallate and EGFR tyrosine kinase inhibitor

One of the mechanisms of the antitumor activity of green tea (−)-epigallocatechin-3-gallate (EGCG) is associated with its effect on epidermal growth factor receptor (EGFR)-mediated signaling transduction pathways. We investigated whether combining EGCG with the EGFR-tyrosine kinase inhibitor (EGFR-T...

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Detalhes bibliográficos
Main Authors: Zhang, Xin, Zhang, Hongzheng, Tighiouart, Mourad, Lee, John E., Shin, Hyung J., Khuri, Fadlo R., Yang, Chung S., Chen, Zhuo (Georgia), Shin, Dong M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2555987/
https://ncbi.nlm.nih.gov/pubmed/18546267
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ijc.23585
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