Acquired resistance to EGFR tyrosine kinase inhibitors alters the metabolism of human head and neck squamous carcinoma cells and xenograft tumours

BACKGROUND: Acquired resistance to molecularly targeted therapeutics is a key challenge in personalised cancer medicine, highlighting the need for identifying the underlying mechanisms and early biomarkers of relapse, in order to guide subsequent patient management. METHODS: Here we use human head a...

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Detalles Bibliográficos
Publicado en:Br J Cancer
Main Authors: Beloueche-Babari, M, Box, C, Arunan, V, Parkes, H G, Valenti, M, De Haven Brandon, A, Jackson, L E, Eccles, S A, Leach, M O
Formato: Artigo
Idioma:Inglês
Publicado: Nature Publishing Group 2015
Assuntos:
Translational Therapeutics
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4385966/
https://ncbi.nlm.nih.gov/pubmed/25742484
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2015.86
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