SKLB188 inhibits the growth of head and neck squamous cell carcinoma by suppressing EGFR signalling

BACKGROUND: Overexpression of epidermal growth factor receptor (EGFR) occurs in approximately 90% of head and neck squamous cell carcinoma (HNSCC), and is correlated with poor prognosis. Thus, targeting EGFR is a promising strategy for treatment of HNSCC. Several small molecule EGFR inhibitors have...

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Bibliografiske detaljer
Udgivet i:Br J Cancer
Main Authors: Barzegar, Mansoureh, Ma, Shuang, Zhang, Chao, Chen, Xin, Gu, Ying, Shang, Chaowei, Jiang, Xiaojuan, Yang, Jiao, Nathan, Cherie-Ann, Yang, Shengyong, Huang, Shile
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group 2017
Fag:
Translational Therapeutics
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674107/
https://ncbi.nlm.nih.gov/pubmed/28873083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/bjc.2017.298
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