Dual inhibition of EGFR and VEGFR pathways in combination with irradiation: antitumour supra-additive effects on human head and neck cancer xenografts

The aim of this study was to investigate the effects of combining antiangiogenic treatment, epidermal growth factor receptor (EGFR) targeting and irradiation (RT). We evaluated AZD2171, a highly potent, orally active, vascular endothelial growth factor (VEGF) signalling inhibitor, gefitinib, an EGFR...

Celý popis

Uloženo v:
Podrobná bibliografie
Hlavní autoři: Bozec, A, Formento, P, Lassalle, S, Lippens, C, Hofman, P, Milano, G
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group 2007
Témata:
Translational Therapeutics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC2359670/
https://ncbi.nlm.nih.gov/pubmed/17592499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjc.6603791
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky