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A Gating Charge Transfer Center in Voltage Sensors

Voltage sensors regulate the conformations of voltage-dependent ion channels and enzymes. Their nearly switch-like response as a function of membrane voltage comes from the movement of positively charged amino acids, arginine or lysine, across the membrane field. We used mutations with natural and u...

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Bibliografiske detaljer
Main Authors: Tao, Xiao, Lee, Alice, Limapichat, Walrati, Dougherty, Dennis A., MacKinnon, Roderick
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2869078/
https://ncbi.nlm.nih.gov/pubmed/20360102
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1126/science.1185954
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