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Esperamicins, a class of potent antitumor antibiotics: mechanism of action.

The esperamicins represent a class of antitumor antibiotics characterized by an unusual chemical core structure and extremely potent cytotoxicity. The mechanism by which these drugs produce cytotoxicity was investigated and found to be related to the formation of single- and double-strand DNA breaks...

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Detaylı Bibliyografya
Yayımlandı:Proc Natl Acad Sci U S A
Asıl Yazarlar: Long, B H, Golik, J, Forenza, S, Ward, B, Rehfuss, R, Dabrowiak, J C, Catino, J J, Musial, S T, Brookshire, K W, Doyle, T W
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 1989
Konular:
Online Erişim:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286391/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2643098/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.1.2
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