Esperamicins, a class of potent antitumor antibiotics: mechanism of action.
The esperamicins represent a class of antitumor antibiotics characterized by an unusual chemical core structure and extremely potent cytotoxicity. The mechanism by which these drugs produce cytotoxicity was investigated and found to be related to the formation of single- and double-strand DNA breaks...
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| Publicat a: | Proc Natl Acad Sci U S A |
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| Autors principals: | , , , , , , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1989
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC286391/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/2643098/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.86.1.2 |
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