Cyclic polyamides for recognition in the minor groove of DNA.
Small molecules that specifically bind with high affinity to any designated DNA sequence in the human genome would be useful tools in molecular biology and potentially in human medicine. Simple rules have been developed to rationally alter the sequence specificity of minor groove-binding polyamides...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1995
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC40802/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/7479790/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.92.22.10389 |
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