The Epstein-Barr Virus (EBV)-Encoded Protein Kinase, EBV-PK, but Not the Thymidine Kinase (EBV-TK), Is Required for Ganciclovir and Acyclovir Inhibition of Lytic Viral Production

Ganciclovir (GCV) and acyclovir (ACV) are guanine nucleoside analogues that inhibit lytic herpesvirus replication. GCV and ACV must be monophosphorylated by virally encoded enzymes to be converted into nucleotides and incorporated into viral DNA. However, whether GCV and/or ACV phosphorylation in Ep...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Main Authors: Meng, Qiao, Hagemeier, Stacy R., Fingeroth, Joyce D., Gershburg, Edward, Pagano, Joseph S., Kenney, Shannon C.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology (ASM) 2010
Fag:
Genome Replication and Regulation of Viral Gene Expression
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863746/
https://ncbi.nlm.nih.gov/pubmed/20181711
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.02487-09
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker