Effects of Maribavir and Selected Indolocarbazoles on Epstein-Barr Virus Protein Kinase BGLF4 and on Viral Lytic Replication

The human cytomegalovirus (HCMV) homolog of the Epstein-Barr virus (EBV) protein kinase (PK), UL97, is inhibited by maribavir (1263W94) and selected indolocarbazoles. Here we show that only one of these indolocarbazoles (K252a), but not maribavir, inhibits autophosphorylation of the EBV PK, BGLF4. H...

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Bibliografiske detaljer
Main Authors: Gershburg, Edward, Hong, Ke, Pagano, Joseph S.
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2004
Fag:
Antiviral Agents
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC400567/
https://ncbi.nlm.nih.gov/pubmed/15105156
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.48.5.1900-1903.2004
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