The Cellular Ataxia Telangiectasia-Mutated Kinase Promotes Epstein-Barr Virus Lytic Reactivation in Response to Multiple Different Types of Lytic Reactivation-Inducing Stimuli

The Epstein-Barr virus (EBV) latent-to-lytic switch is mediated by the viral proteins BZLF1 (Z), BRLF1 (R), and BRRF1 (Na). Since we previously showed that DNA-damaging agents (including chemotherapy and irradiation) can induce EBV lytic reactivation and recently demonstrated that wild-type p53 cont...

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Bibliographic Details
Main Authors: Hagemeier, Stacy R., Barlow, Elizabeth A., Meng, Qiao, Kenney, Shannon C.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2012
Subjects:
Genome Replication and Regulation of Viral Gene Expression
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3503132/
https://ncbi.nlm.nih.gov/pubmed/23015717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01850-12
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