Combinations of Mutations in the Connection Domain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Assessing the Impact on Nucleoside and Nonnucleoside Reverse Transcriptase Inhibitor Resistance

Recent reports have described the effect of mutations in the connection and RNase H domains of reverse transcriptase (RT) on nucleoside and nonnucleoside reverse transcriptase inhibitor (NRTI and NNRTI, respectively) resistance in the presence of thymidine analog resistance mutations (TAMs) and NNRT...

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Detalhes bibliográficos
Main Authors: Gupta, Soumi, Fransen, Signe, Paxinos, Ellen E., Stawiski, Eric, Huang, Wei, Petropoulos, Christos J.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Antiviral Agents
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863632/
https://ncbi.nlm.nih.gov/pubmed/20194692
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00870-09
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