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The K101P and K103R/V179D Mutations in Human Immunodeficiency Virus Type 1 Reverse Transcriptase Confer Resistance to Nonnucleoside Reverse Transcriptase Inhibitors

Genotypic patterns associated with nonnucleoside reverse transcriptase inhibitor (NNRTI) resistance in the absence of well-characterized resistance mutations were identified using a database (n > 47,000) of phenotype-genotype data. Among samples with no known NNRTI mutations, the most resistant s...

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Detalles Bibliográficos
Autores principales: Parkin, Neil T., Gupta, Soumi, Chappey, Colombe, Petropoulos, Christos J.
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Microbiology 2006
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC1346823/
https://ncbi.nlm.nih.gov/pubmed/16377709
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.50.1.351-354.2006
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