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Novel Nonnucleoside Inhibitors That Select Nucleoside Inhibitor Resistance Mutations in Human Immunodeficiency Virus Type 1 Reverse Transcriptase

Mutations in and around the catalytic site of the reverse transcriptase (RT) of human immunodeficiency virus type 1 (HIV-1) are associated with resistance to nucleoside RT inhibitors (NRTIs), whereas changes in the hydrophobic pocket of the RT are attributed to nonnucleoside RT inhibitor (NNRTI) res...

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Hlavní autoři: Zhang, Zhijun, Walker, Michelle, Xu, Wen, Shim, Jae Hoon, Girardet, Jean-Luc, Hamatake, Robert K., Hong, Zhi
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2006
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1538665/
https://ncbi.nlm.nih.gov/pubmed/16870771
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00127-06
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