Human Immunodeficiency Virus Mutagenesis during Antiviral Therapy: Impact of Drug-Resistant Reverse Transcriptase and Nucleoside and Nonnucleoside Reverse Transcriptase Inhibitors on Human Immunodeficiency Virus Type 1 Mutation Frequencies

The development of antiviral drug resistance is an important problem in the treatment of human immunodeficiency virus type 1 (HIV-1) infection. Potent antiretroviral therapy is currently used for treatment, and typically consists of at least two reverse transcriptase (RT) inhibitors. We have previou...

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Bibliographic Details
Main Authors: Chen, Renxiang, Yokoyama, Masaru, Sato, Hironori, Reilly, Cavan, Mansky, Louis M.
Format: Artigo
Language:Inglês
Published: American Society for Microbiology 2005
Subjects:
Vaccines and Antiviral Agents
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC1212631/
https://ncbi.nlm.nih.gov/pubmed/16140780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.18.12045-12057.2005
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