Multiple Genetic Pathways Involving Amino Acid Position 143 of HIV-1 Integrase Are Preferentially Associated with Specific Secondary Amino Acid Substitutions and Confer Resistance...

af Huang, Wei, Frantzell, Arne, Fransen, Signe, Petropoulos, Christos J.
Udgivet 2013

Substitutions at Amino Acid Positions 143, 148, and 155 of HIV-1 Integrase Define Distinct Genetic Barriers to Raltegravir Resistance In Vivo

af Fransen, Signe, Gupta, Soumi, Frantzell, Arne, Petropoulos, Christos J., Huang, Wei
Udgivet 2012

Longitudinal Analysis of Raltegravir Susceptibility and Integrase Replication Capacity of Human Immunodeficiency Virus Type 1 during Virologic Failure

af Fransen, Signe, Karmochkine, Marina, Huang, Wei, Weiss, Laurence, Petropoulos, Christos J., Charpentier, Charlotte
Udgivet 2009

Combinations of Mutations in the Connection Domain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase: Assessing the Impact on Nucleoside and Nonnucleoside Reverse Transc...

af Gupta, Soumi, Fransen, Signe, Paxinos, Ellen E., Stawiski, Eric, Huang, Wei, Petropoulos, Christos J.
Udgivet 2010

Mutational Pathways and Genetic Barriers to CXCR4-Mediated Entry by Human Immunodeficiency Virus Type 1

af Huang, Wei, Frantzell, Arne, Toma, Jonathan, Fransen, Signe, Whitcomb, Jeannette M., Stawiski, Eric, Petropoulos, Christos J.
Udgivet 2010

Loss of Raltegravir Susceptibility by Human Immunodeficiency Virus Type 1 Is Conferred via Multiple Nonoverlapping Genetic Pathways

af Fransen, Signe, Gupta, Soumi, Danovich, Robert, Hazuda, Daria, Miller, Michael, Witmer, Marc, Petropoulos, Christos J., Huang, Wei
Udgivet 2009

Performance of the Abbott RealTime HIV-1 Viral Load Assay Is Not Impacted by Integrase Inhibitor Resistance-Associated Mutations

af Young, Thomas P., Cloherty, Gavin, Fransen, Signe, Napolitano, Laura, Swanson, Priscilla, Herman, Christine, Parkin, Neil T., Hackett, John
Udgivet 2011

Suppression of Dualtropic Human Immunodeficiency Virus Type 1 by the CXCR4 Antagonist AMD3100 Is Associated with Efficiency of CXCR4 Use and Baseline Virus Composition

af Fransen, Signe, Bridger, Gary, Whitcomb, Jeannette M., Toma, Jonathan, Stawiski, Eric, Parkin, Neil, Petropoulos, Christos J., Huang, Wei
Udgivet 2008

Coreceptor Tropism Can Be Influenced by Amino Acid Substitutions in the gp41 Transmembrane Subunit of Human Immunodeficiency Virus Type 1 Envelope Protein

af Huang, Wei, Toma, Jonathan, Fransen, Signe, Stawiski, Eric, Reeves, Jacqueline D., Whitcomb, Jeannette M., Parkin, Neil, Petropoulos, Christos J.
Udgivet 2008

Evolution of Integrase Resistance During Failure of Integrase Inhibitor-Based Antiretroviral Therapy

af Hatano, Hiroyu, Lampiris, Harry, Fransen, Signe, Gupta, Soumi, Huang, Wei, Hoh, Rebecca, Martin, Jeffrey N., Lalezari, Jacob, Bangsberg, David, Petropoulos, Christos, Deeks, Steven G.
Udgivet 2010

Development and Characterization of a Novel Single-Cycle Recombinant-Virus Assay To Determine Human Immunodeficiency Virus Type 1 Coreceptor Tropism

af Whitcomb, Jeannette M., Huang, Wei, Fransen, Signe, Limoli, Kay, Toma, Jonathan, Wrin, Terri, Chappey, Colombe, Kiss, Linda D. B., Paxinos, Ellen E., Petropoulos, Christos J.
Udgivet 2007

Connection Domain Mutations in HIV-1 Reverse Transcriptase Do Not Impact Etravirine Susceptibility and Virologic Responses to Etravirine-Containing Regimens

af Gupta, Soumi, Vingerhoets, Johan, Fransen, Signe, Tambuyzer, Lotke, Azijn, Hilde, Frantzell, Arne, Paredes, Roger, Coakley, Eoin, Nijs, Steven, Clotet, Bonaventura, Petropoulos, Christos J., Schapiro, Jonathan, Huang, Wei, Picchio, Gaston
Udgivet 2011

Characterization of Human Immunodeficiency Virus Type 1 Populations Containing CXCR4-Using Variants from Recently Infected Individuals

af Huang, Wei, Toma, Jonathan, Stawiski, Eric, Fransen, Signe, Wrin, Terri, Parkin, Neil, Whitcomb, Jeannette M., Coakley, Eoin, Hecht, Frederick M., Deeks, Steven G., Gandhi, Rajesh T., Eshleman, Susan H., Petropoulos, Christos J.
Udgivet 2009

Coreceptor Tropism in Human Immunodeficiency Virus Type 1 Subtype D: High Prevalence of CXCR4 Tropism and Heterogeneous Composition of Viral Populations

af Huang, Wei, Eshleman, Susan H., Toma, Jonathan, Fransen, Signe, Stawiski, Eric, Paxinos, Ellen E., Whitcomb, Jeannette M., Young, Alicia M., Donnell, Deborah, Mmiro, Francis, Musoke, Philippa, Guay, Laura A., Jackson, J. Brooks, Parkin, Neil T., Petropoulos, Christos J.
Udgivet 2007

Machine learning enables detection of early-stage colorectal cancer by whole-genome sequencing of plasma cell-free DNA

af Wan, Nathan, Weinberg, David, Liu, Tzu-Yu, Niehaus, Katherine, Ariazi, Eric A., Delubac, Daniel, Kannan, Ajay, White, Brandon, Bailey, Mitch, Bertin, Marvin, Boley, Nathan, Bowen, Derek, Cregg, James, Drake, Adam M., Ennis, Riley, Fransen, Signe, Gafni, Erik, Hansen, Loren, Liu, Yaping, Otte, Gabriel L., Pecson, Jennifer, Rice, Brandon, Sanderson, Gabriel E., Sharma, Aarushi, St. John, John, Tang, Catherina, Tzou, Abraham, Young, Leilani, Putcha, Girish, Haque, Imran S.
Udgivet i BMC Cancer (2019)