Loss of Raltegravir Susceptibility by Human Immunodeficiency Virus Type 1 Is Conferred via Multiple Nonoverlapping Genetic Pathways

The human immunodeficiency virus type 1 (HIV-1) integrase mutations N155H and Q148R(H)(K) that reduce susceptibility to the integrase inhibitor raltegravir have been identified in patients failing treatment regimens containing raltegravir. Whether these resistance mutations occur individually or in...

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Bibliografiska uppgifter
Huvudupphovsmän: Fransen, Signe, Gupta, Soumi, Danovich, Robert, Hazuda, Daria, Miller, Michael, Witmer, Marc, Petropoulos, Christos J., Huang, Wei
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2009
Ämnen:
Vaccines and Antiviral Agents
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2772690/
https://ncbi.nlm.nih.gov/pubmed/19759152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01168-09
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