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A Comprehensive Model That Explains the Regulation of Phospholipase D2 Activity by Phosphorylation-Dephosphorylation

We report here that the enzymatic activity of phospholipase D2 (PLD2) is regulated by phosphorylation-dephosphorylation. Phosphatase treatment of PLD2-overexpressing cells showed a biphasic nature of changes in activity that indicated the existence of “activator” and “inhibitory” sites. We identifie...

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Detalhes bibliográficos
Main Authors: Henkels, Karen M., Peng, Hong-Juan, Frondorf, Kathleen, Gomez-Cambronero, Julian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863589/
https://ncbi.nlm.nih.gov/pubmed/20176813
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.01239-09
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