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Irreversible Inhibition of DNA Polymerase β by an Oxidized Abasic Lesion
[Image: see text] DNA damage is a source of carcinogenicity and is also the source of cytotoxicity of γ-radiolysis and antitumor agents, such as the enediynes. The dioxobutane lesion (DOB) is produced by a variety of DNA damaging agents, including the aforementioned. Repair of DOB is important for m...
Tallennettuna:
| Päätekijät: | , |
|---|---|
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2010
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2863033/ https://ncbi.nlm.nih.gov/pubmed/20334373 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja101372c |
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