Caricamento...
Irreversible Inhibition of DNA Polymerase β by Small Molecule Mimics of a DNA Lesion
Abasic sites are ubiquitous DNA lesions that are mutagenic and cytotoxic but are removed by the base excision repair pathway. DNA polymerase β carries out two of the four steps during base excision repair, including a lyase reaction that removes the abasic site from DNA following incision of its 5′-...
Salvato in:
| Autori principali: | , , , , , , |
|---|---|
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
|
| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4047187/ https://ncbi.nlm.nih.gov/pubmed/24517090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja411733s |
| Tags: |
Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !
|