Загрузка...
Irreversible Inhibition of DNA Polymerase β by Small Molecule Mimics of a DNA Lesion
Abasic sites are ubiquitous DNA lesions that are mutagenic and cytotoxic but are removed by the base excision repair pathway. DNA polymerase β carries out two of the four steps during base excision repair, including a lyase reaction that removes the abasic site from DNA following incision of its 5′-...
Сохранить в:
| Главные авторы: | , , , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
2014
|
| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4047187/ https://ncbi.nlm.nih.gov/pubmed/24517090 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja411733s |
| Метки: |
Добавить метку
Нет меток, Требуется 1-ая метка записи!
|