A carregar...

Irreversible Inhibition of DNA Polymerase β by Small Molecule Mimics of a DNA Lesion

Abasic sites are ubiquitous DNA lesions that are mutagenic and cytotoxic but are removed by the base excision repair pathway. DNA polymerase β carries out two of the four steps during base excision repair, including a lyase reaction that removes the abasic site from DNA following incision of its 5′-...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Main Authors: Arian, Dumitru, Hedayati, Mohammad, Zhou, Haoming, Bilis, Zoe, Chen, Karen, DeWeese, Theodore L., Greenberg, Marc M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4047187/
https://ncbi.nlm.nih.gov/pubmed/24517090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ja411733s
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!