Inhibition of the soluble epoxide hydrolase attenuates monocrotaline-induced pulmonary hypertension in rats

OBJECTIVES: The soluble epoxide hydrolase (sEH) metabolizes epoxyeicosatrienoic acids (EETs) to their less active dihydroxy derivatives. Because EETs have anti-inflammatory properties, we determined whether or not inhibition of sEH attenuates disease development in the monocrotaline model of pulmona...

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Detaylı Bibliyografya
Asıl Yazarlar: Revermann, Marc, Barbosa-Sicard, Eduardo, Dony, Eva, Schermuly, Ralph T., Morisseau, Christophe, Geisslinger, Gerd, Fleming, Ingrid, Hammock, Bruce D., Brandes, Ralf P.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2009
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Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC2863009/
https://ncbi.nlm.nih.gov/pubmed/19226702
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