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Tuning the Insertion Properties of pHLIP
The pH (low) insertion peptide (pHLIP) has exceptional characteristics: at neutral pH it is an unstructured monomer in solution or when bound to lipid bilayer surfaces, and it inserts across a lipid bilayer as a monomeric alpha-helix at acidic pH. The peptide targets acidic tissues in vivo, and may...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2009
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2862812/ https://ncbi.nlm.nih.gov/pubmed/19766589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bbamem.2009.08.023 |
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