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2-Cyano-3,10-dioxooleana-1,9(11)-dien-28-oic acid anhydride. A novel and highly potent anti-inflammatory and cytoprotective agent

2-Cyano-3,10-dioxooleana-1,9(11)-dien-28-oic acid anhydride (CDDO anhydride) has been synthesized, which is the first example of an oleanane triterpenoid anhydride. CDDO anhydride shows potency similar to or higher than the corresponding acid (CDDO) in various in vitro and in vivo assays related to...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Honda, Tadashi, Padegimas, Eric M., David, Emilie, Sundararajan, Chitra, Liby, Karen T., Williams, Charlotte, Sporn, Michael B., Visnick, Melean
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862379/
https://ncbi.nlm.nih.gov/pubmed/20188548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.02.007
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