The Methyl Ester of 2-Cyano-3,12-Dioxooleana-1,9-Dien-28-Oic Acid Reduces Endometrial Lesions Development by Modulating the NFkB and Nrf2 Pathways

Endometriosis is a common gynecological disease. Here, we aimed to investigate the anti-fibrotic, anti-inflammatory, and anti-oxidative role of the methyl ester of 2-cyano-3,12-dioxooleana-1,9-dien-28-oic acid (CDDO-Me) on endometriosis. An endometriosis rat model was constructed by intraperitoneall...

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Detalhes bibliográficos
Publicado no:Int J Mol Sci
Main Authors: Siracusa, Rosalba, D’Amico, Ramona, Cordaro, Marika, Peritore, Alessio Filippo, Genovese, Tiziana, Gugliandolo, Enrico, Crupi, Rosalia, Impellizzeri, Daniela, Cuzzocrea, Salvatore, Fusco, Roberta, Di Paola, Rosanna
Formato: Artigo
Idioma:Inglês
Publicado em: MDPI 2021
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8069675/
https://ncbi.nlm.nih.gov/pubmed/33924360
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ijms22083991
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