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2-Cyano-3,10-dioxooleana-1,9(11)-dien-28-oic acid anhydride. A novel and highly potent anti-inflammatory and cytoprotective agent

2-Cyano-3,10-dioxooleana-1,9(11)-dien-28-oic acid anhydride (CDDO anhydride) has been synthesized, which is the first example of an oleanane triterpenoid anhydride. CDDO anhydride shows potency similar to or higher than the corresponding acid (CDDO) in various in vitro and in vivo assays related to...

詳細記述

保存先:
書誌詳細
主要な著者: Honda, Tadashi, Padegimas, Eric M., David, Emilie, Sundararajan, Chitra, Liby, Karen T., Williams, Charlotte, Sporn, Michael B., Visnick, Melean
フォーマット: Artigo
言語:Inglês
出版事項: 2010
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862379/
https://ncbi.nlm.nih.gov/pubmed/20188548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.02.007
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