2-Cyano-3,10-dioxooleana-1,9(11)-dien-28-oic acid anhydride. A novel and highly potent anti-inflammatory and cytoprotective agent

2-Cyano-3,10-dioxooleana-1,9(11)-dien-28-oic acid anhydride (CDDO anhydride) has been synthesized, which is the first example of an oleanane triterpenoid anhydride. CDDO anhydride shows potency similar to or higher than the corresponding acid (CDDO) in various in vitro and in vivo assays related to...

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Bibliografiske detaljer
Main Authors: Honda, Tadashi, Padegimas, Eric M., David, Emilie, Sundararajan, Chitra, Liby, Karen T., Williams, Charlotte, Sporn, Michael B., Visnick, Melean
Format: Artigo
Sprog:Inglês
Udgivet: 2010
Fag:
Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2862379/
https://ncbi.nlm.nih.gov/pubmed/20188548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bmcl.2010.02.007
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