Small Molecule Kinase Inhibitors Provide Insight into Mps1 Cell Cycle Function

Mps1, a dual-specificity kinase, is required for the proper functioning of the spindle assembly checkpoint and the maintenance of chromosomal stability. As Mps1 function has been implicated in numerous phases of the cell cycle, it is expected the development of a potent, selective small molecule inh...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Kwiatkowski, Nicholas, Jelluma, Nannette, Filippakopoulos, Panagis, Soundararajan, Meera, Manak, Michael S., Kwon, Mijung, Choi, Hwan Geun, Sim, Taebo, Deveraux, Quinn L., Rottmann, Sabine, Pellman, David, Shah, Jagesh V., Kops, Geert J.P.L., Knapp, Stefan, Gray, Nathanael S.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2010
Gaiak:
Article
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857554/
https://ncbi.nlm.nih.gov/pubmed/20383151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nchembio.345
Etiketak: Etiketa erantsi
Etiketarik gabe, Izan zaitez lehena erregistro honi etiketa jartzen!

Antzeko izenburuak