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Aurora B potentiates Mps1 activation to ensure rapid checkpoint establishment at the onset of mitosis
The mitotic checkpoint prevents mitotic exit until all chromosomes are attached to spindle microtubules. Aurora B kinase indirectly invokes this checkpoint by destabilizing incorrect attachments; however, a more direct role remains controversial. In contrast, activity of the kinase Mps1 is indispens...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Nature Publishing Group
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3113227/ https://ncbi.nlm.nih.gov/pubmed/21587233 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms1319 |
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