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Negative feedback at kinetochores underlies a responsive spindle checkpoint signal

Kinetochores are specialised multi-protein complexes that play a crucial role in maintaining genome stability 1. They bridge attachments between chromosomes and microtubules during mitosis and they activate the spindle assembly checkpoint (SAC) to arrest division until all chromosomes are attached 2...

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Detalhes bibliográficos
Publicado no:Nat Cell Biol
Main Authors: Nijenhuis, Wilco, Vallardi, Giulia, van den Dikkenberg, Antoinette, Kops, Geert JPL, Saurin, Adrian T
Formato: Artigo
Idioma:Inglês
Publicado em: 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6485516/
https://ncbi.nlm.nih.gov/pubmed/25402682
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3065
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