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Negative feedback at kinetochores underlies a responsive spindle checkpoint signal
Kinetochores are specialised multi-protein complexes that play a crucial role in maintaining genome stability 1. They bridge attachments between chromosomes and microtubules during mitosis and they activate the spindle assembly checkpoint (SAC) to arrest division until all chromosomes are attached 2...
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| Pubblicato in: | Nat Cell Biol |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2014
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6485516/ https://ncbi.nlm.nih.gov/pubmed/25402682 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncb3065 |
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