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ZW10 links mitotic checkpoint signaling to the structural kinetochore

The mitotic checkpoint ensures that chromosomes are divided equally between daughter cells and is a primary mechanism preventing the chromosome instability often seen in aneuploid human tumors. ZW10 and Rod play an essential role in this checkpoint. We show that in mitotic human cells ZW10 resides i...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Kops, Geert J.P.L., Kim, Yumi, Weaver, Beth A.A., Mao, Yinghui, McLeod, Ian, Yates, John R., Tagaya, Mitsuo, Cleveland, Don W.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The Rockefeller University Press 2005
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC1351127/
https://ncbi.nlm.nih.gov/pubmed/15824131
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200411118
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