Microtubule capture by CENP-E silences BubR1-dependent mitotic checkpoint signaling

The mitotic checkpoint is the major cell cycle control mechanism for maintaining chromosome content in multicellular organisms. Prevention of premature onset of anaphase requires activation at unattached kinetochores of the BubR1 kinase, which acts with other components to generate a diffusible “sto...

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Bibliographic Details
Main Authors: Mao, Yinghui, Desai, Arshad, Cleveland, Don W.
Format: Artigo
Language:Inglês
Published: The Rockefeller University Press 2005
Subjects:
Research Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC2171436/
https://ncbi.nlm.nih.gov/pubmed/16144904
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.200505040
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