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CENP-E–dependent BubR1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint

How the state of spindle microtubule capture at the kinetochore is translated into mitotic checkpoint signaling remains largely unknown. In this paper, we demonstrate that the kinetochore-associated mitotic kinase BubR1 phosphorylates itself in human cells and that this autophosphorylation is depend...

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Detalhes bibliográficos
Main Authors: Guo, Yige, Kim, Christine, Ahmad, Sana, Zhang, Jiayin, Mao, Yinghui
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3410423/
https://ncbi.nlm.nih.gov/pubmed/22801780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201202152
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