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CENP-E–dependent BubR1 autophosphorylation enhances chromosome alignment and the mitotic checkpoint
How the state of spindle microtubule capture at the kinetochore is translated into mitotic checkpoint signaling remains largely unknown. In this paper, we demonstrate that the kinetochore-associated mitotic kinase BubR1 phosphorylates itself in human cells and that this autophosphorylation is depend...
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| Главные авторы: | , , , , |
|---|---|
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
The Rockefeller University Press
2012
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3410423/ https://ncbi.nlm.nih.gov/pubmed/22801780 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1083/jcb.201202152 |
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