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Microtubule attachment and spindle assembly checkpoint signaling at the kinetochore

In eukaryotes, chromosome segregation during cell division is facilitated by the kinetochore, an assembly of proteins built on centromeric DNA. The kinetochore attaches chromosomes to spindle microtubules, modulates the stability of these attachments, and relays microtubule-binding status to the spi...

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Detalhes bibliográficos
Main Authors: Foley, Emily A., Kapoor, Tarun M.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762224/
https://ncbi.nlm.nih.gov/pubmed/23258294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3494
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