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Stable kinetochore–microtubule attachment is sufficient to silence the spindle assembly checkpoint in human cells

During mitosis, duplicated sister chromatids attach to microtubules emanating from opposing sides of the bipolar spindle through large protein complexes called kinetochores. In the absence of stable kinetochore–microtubule attachments, a cell surveillance mechanism known as the spindle assembly chec...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Tauchman, Eric C., Boehm, Frederick J., DeLuca, Jennifer G.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4686653/
https://ncbi.nlm.nih.gov/pubmed/26620470
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms10036
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