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Microtubule attachment and spindle assembly checkpoint signaling at the kinetochore

In eukaryotes, chromosome segregation during cell division is facilitated by the kinetochore, an assembly of proteins built on centromeric DNA. The kinetochore attaches chromosomes to spindle microtubules, modulates the stability of these attachments, and relays microtubule-binding status to the spi...

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Détails bibliographiques
Auteurs principaux: Foley, Emily A., Kapoor, Tarun M.
Format: Artigo
Langue:Inglês
Publié: 2013
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3762224/
https://ncbi.nlm.nih.gov/pubmed/23258294
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrm3494
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