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Leader of the SAC: molecular mechanisms of Mps1/TTK regulation in mitosis

Discovered in 1991 in a screen for genes involved in spindle pole body duplication, the monopolar spindle 1 (Mps1) kinase has since claimed a central role in processes that ensure error-free chromosome segregation. As a result, Mps1 kinase activity has become an attractive candidate for pharmaceutic...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Open Biol
Main Authors: Pachis, Spyridon T., Kops, Geert J. P. L.
Format: Artigo
Jezik:Inglês
Izdano: The Royal Society 2018
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6119859/
https://ncbi.nlm.nih.gov/pubmed/30111590
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1098/rsob.180109
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