Autophagy promotes tumor cell survival and restricts necrosis, inflammation, and tumorigenesis

Defective apoptosis renders immortalized epithelial cells highly tumorigenic, but how this is impacted by other common tumor mutations is not known. In apoptosis-defective cells, inhibition of autophagy by AKT activation or by allelic disruption of beclin1 confers sensitivity to metabolic stress by...

Descripción completa

Guardado en:
Detalles Bibliográficos
Autores principales: Degenhardt, Kurt, Mathew, Robin, Beaudoin, Brian, Bray, Kevin, Anderson, Diana, Chen, Guanghua, Mukherjee, Chandreyee, Shi, Yufang, Gélinas, Céline, Fan, Yongjun, Nelson, Deirdre A., Jin, Shengkan, White, Eileen
Formato: Artigo
Lenguaje:Inglês
Publicado: 2006
Materias:
Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2857533/
https://ncbi.nlm.nih.gov/pubmed/16843265
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ccr.2006.06.001
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares