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Autophagy suppresses tumor progression by limiting chromosomal instability
Autophagy is a bulk degradation process that promotes survival under metabolic stress, but it can also be a means of cell death if executed to completion. Monoallelic loss of the essential autophagy gene beclin1 causes susceptibility to metabolic stress, but also promotes tumorigenesis. This raises...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Cold Spring Harbor Laboratory Press
2007
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC1877749/ https://ncbi.nlm.nih.gov/pubmed/17510285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1101/gad.1545107 |
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