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Role of the Polarity Determinant Crumbs in Suppressing Mammalian Epithelial Tumor Progression

Most tumors are epithelial-derived, and although disruption of polarity and aberrant cellular junction formation is a poor prognosticator in human cancer, the role of polarity determinants in oncogenesis is poorly understood. Using in vivo selection, we identified a mammalian orthologue of the Droso...

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Detalhes bibliográficos
Main Authors: Karp, Cristina M., Tan, Ting Ting, Mathew, Robin, Nelson, Deidre, Mukherjee, Chandreyee, Degenhardt, Kurt, Karantza-Wadsworth, Vassiliki, White, Eileen
Formato: Artigo
Idioma:Inglês
Publicado em: 2008
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2696887/
https://ncbi.nlm.nih.gov/pubmed/18519669
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6814
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