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Role of the Polarity Determinant Crumbs in Suppressing Mammalian Epithelial Tumor Progression
Most tumors are epithelial-derived, and although disruption of polarity and aberrant cellular junction formation is a poor prognosticator in human cancer, the role of polarity determinants in oncogenesis is poorly understood. Using in vivo selection, we identified a mammalian orthologue of the Droso...
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Main Authors: | , , , , , , , |
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Format: | Artigo |
Jezik: | Inglês |
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2008
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Teme: | |
Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2696887/ https://ncbi.nlm.nih.gov/pubmed/18519669 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-07-6814 |
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