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Human DNA methylomes at base resolution show widespread epigenomic differences
DNA cytosine methylation is a central epigenetic modification that plays essential roles in cellular processes including genome regulation, development and disease. Here we present the first genome-wide, single-base resolution maps of methylated cytosines in a mammalian genome, from both human embry...
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| Main Authors: | , , , , , , , , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2009
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| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2857523/ https://ncbi.nlm.nih.gov/pubmed/19829295 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature08514 |
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