Subcutaneous Nogo Receptor Removes Brain Amyloid-β and Improves Spatial Memory in Alzheimer's Transgenic Mice

The production and aggregation of cerebral amyloid-β (Aβ) peptide are thought to play a causal role in Alzheimer's disease (AD). Previously, we found that the Nogo-66 receptor (NgR) interacts physically with both Aβ and the amyloid precursor protein (APP). The inverse correlation of Aβ levels w...

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Bibliografiska uppgifter
Huvudupphovsmän: Park, James H., Widi, Gabriel A., Gimbel, David A., Harel, Noam Y., Lee, Daniel H. S., Strittmatter, Stephen M.
Materialtyp: Artigo
Språk:Inglês
Publicerad: Society for Neuroscience 2006
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Articles
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2856604/
https://ncbi.nlm.nih.gov/pubmed/17182778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4504-06.2006
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